faculty pics
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Frank Gu
Assistant Professor
Office: E6 4018
Phone: 519-888-4567 ext. 38605
Email: fxgu@uwaterloo.ca
Degrees: BSc,
Trent University; PhD, Queens; Post-doctoral Fellowship, MIT
Lab Homepage
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Research Interests
Nanotechnology, Nanomedicine, Cancer Therapy, Drug Delivery, Biomaterials, Bioconjugated Chemisry and Bioinformatics
Selected References
- Dhar, S., Gu, F., Langer, R., Farokhzad, O., Lippard, S. (2008) Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA–PEG nanoparticles. Proceeding to the National Academy of Sciences of the United States of America. 105( 45), 2008, 7356 – 7361.
- Karnik, R*., Gu, F*., Basto, P., Cannizzaro, C., Dean, L., Kyei-Manu, W. , Farokhzad, O., Langer, R. (2008) Synthesis of Poly(lactide-co-glycolide)-b-Poly(ethyleneglycol) nanoparticles using hydrodynamic flow focusing. Nano Letters. 8(9):2906-2912.
- Gu, F., Zhang, L., Teply, B., Mann, N., Wang, A., Radovic-Moreno, A., Langer, R., Farokhzad, O. (2008) Self assembly of precisely engineered targeted nanoparticles for screening optimal nanoparticle formulations in vitro and in vivo. Proceeding to the National Academy of Sciences of the United States of America. 105(7):2586-2591.
- Gu, F., Karnik, R., Wang, A., Alexis, F., Levy-Nissenbaum, E., Hong, SP., Langer, R., Farokhzad, OC. (2007) Development of targeted nanoparticles for cancer therapy. Nano Today. 2(3):14-20.
- Gu, F., Neufeld, R., Amsden, B. (2007) Near Zero order release of bioactive cytokines from a biodegradable elastomer: influence of geometry and elastomer mechanical properties. Journal of Controlled Release. 117(1):80-9.
- Gu, F., Amsden, B., Neufeld, R. (2004) Sustained release of vascular endothelial growth factor from alginate beads. Journal Controlled Release. 96 (3):463-472.
Awards and Fellowships
- NSERC Postdoctoral Fellowship
- Japanese Society for the Promotion of Science (JSPS) Summer Fellowship
- NSERC Canada Graduate Scholarship
- NSERC Postgraduate Scholarship
Please note - Professor Gu is a new faculty member and has immediate openings for graduate students in the area of Nanomedicine, Drug delivery and Polymer Engineering. Application details are on-line at:
http://chemeng.uwaterloo.ca/graduate/prospective_students.html