Welcome to Chemical Engineering at the University of Waterloo

Professor Valerie Ward is part of a new global coalition to revolutionize vaccine production with disruptive health technology. The technology is designed to enable local vaccine production, reducing production time from nine days to just one day. A breakthrough that has the potential to save millions of lives and significantly lower the cost of vaccine production.

A research coalition led by the Centre for Process Innovation (CPI) received $2.8 million from the Coalition of Epidemic Preparedness Innovation (CEPI) to fund technology development to combat epidemics and pandemics. The aim is to make small transportable units to manufacture vaccines, making vaccines more accessible and better able to deal with local outbreaks.

Ward is working with researchers and industry partners in Brazil, the UK, and Canada to aid the world in responding more swiftly and equitably to future epidemics and pandemics. 

The grant focuses on developing technology to meet two specific goals. The first is rapid production of vaccines. The second is to decentralize manufacturing so it can be produced at different sites in smaller batches.

Researchers in the Department of Chemical Engineering have developed a new method for engineering bacteria that can be leveraged to improve biomedical applications such as drug delivery, cancer therapy, anti-inflammatory treatments, and vaccine development.

The international research group, led by Professor Yilan Liu, developed a process that enables bacteria to secrete bacterial membrane vesicles (BMVs). BMVs are nanosized bubble-shaped structures naturally released by bacteria. They have significant potential as tools for the development of a variety of therapeutics.  

Currently, the adoption of BMVs has been hindered by low production yields under natural conditions. The technique established by Liu resulted in a 140-fold increase in the secretion of BMVs.

"This advancement in bacterial engineering has the potential to be a transformative platform for next-generation vaccines, therapeutics, and nutrient delivery," says Liu. "This new process could profoundly impact global health by making biomedical treatments more efficient, accessible, and affordable."

The Department of Chemical Engineering is proud to announce the appointment of Professor Evelyn Yim as an NSERC Canada Research Chair in Nanomaterials for Regenerative Medicine.

Yim has also been awarded over $ 1 million to conduct research focusing on understanding and enhancing microenvironments by controlling cell-nanostructure interactions for applications in regenerative medicine.

Her research examines how cells respond to biomaterials, focusing on 2D and 3D systems. The field of regenerative nanomedicine uses nanotechnology to repair or regenerate damaged tissue and organs. She uses principles of engineering and biological science to advance regenerative nanomedicine.

Offering promising solutions for a range of diseases

Yim’s research group is developing different types of nanofabrication materials to mimic natural nanostructures found in the human body to guide cell growth.

Yim conducts pioneering research in nanotopography, cell therapy, and improving the design of neural stem cells.  She has advanced innovations in tissue engineering for vascular and corneal disease.